Journal: World Journal of Surgical Oncology
Article Title: STIM1/SOX2 proteins are co-expressed in the tumor and microenvironmental stromal cells of pancreatic ductal adenocarcinoma and ampullary carcinoma
doi: 10.1186/s12957-024-03356-y
Figure Lengend Snippet: STIM1 immunohistochemical expression in the studied groups. ( a ) A case of normal pancreatic tissue showed weak cytoplasmic STIM1 epithelial expression in the pancreatic duct and focal cytoplasmic STIM1 stromal expression (IHC x200), ( b ) A case of adjacent non-tumor pancreatic tissue showed moderate cytoplasmic STIM1 epithelial expression and focal STIM1 cytoplasmic stromal expression (IHC x100), ( c ) A case of control non-tumor intestinal tissue showed moderate cytoplasmic STIM1 epithelial expression and focal cytoplasmic STIM1 stromal expression (IHC x100), ( d ) A case of primary PDAC showed strong cytoplasmic STIM1 epithelial and stromal expression (IHC x100), ( e ) A case of metastatic PDAC to the liver (on the left side) showed strong cytoplasmic STIM1 epithelial and stromal expression (IHC x100), ( f ) A case of AAC showed strong cytoplasmic STIM1 epithelial and stromal expression (IHC x100)
Article Snippet: Rabbit polyclonal anti-STIM1 diluted as 1:200 (Cat. No. bs-8526R) obtained from BIOSS, Woburn, Massachusett, USA, rabbit polyclonal anti-SOX2 diluted as 1:250 (Cat. No. GB11249) obtained from Service bio, Wuhan, China, and a rabbit monoclonal anti-BCL2 antibody ready to use, (Cat. No. ab32124) obtained from Abcam, Cambridge, UK were used.
Techniques: Immunohistochemical staining, Expressing, Control